What is the Boc-N-methyl-L-valine?

Boc-N-methyl-L-valine is White powder, while it's Molecular Formula is C11H21NO4. White powder N-Boc-N-methyl-L-valine is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent.

What is the CAS number for Boc-N-methyl-L-valine?

The CAS number of Boc-N-methyl-L-valine is 45170-31-8.

What is the Boc-N-methyl-L-valine?

Boc-N-methyl-L-valine is White powder, while it's Molecular Formula is C11H21NO4. White powder N-Boc-N-methyl-L-valine is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent.

What is the CAS number for Boc-N-methyl-L-valine?

The CAS number of Boc-N-methyl-L-valine is 45170-31-8.

45170-31-8

Product NameBoc-N-Me-Val
Molecular FormulaC₁₁H₂₁NO₄
Molecular Weight231.292
Purity99%
AppearanceWhite powder

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Product Details

Quick Details

CasNo： 45170-31-8
Molecular Formula： C₁₁H₂₁NO₄
Appearance： White powder
Purity： 99%

Buy High Grade Wholesale Boc-N-Me-Val 45170-31-8 Fast Delivery

Molecular Formula:C11H21NO4
Molecular Weight:231.292
Appearance/Colour:White powder
Vapor Pressure:5.74E-05mmHg at 25°C
Melting Point:52.9oC (dec.)
Refractive Index:1.466
Boiling Point:322.4 °C at 760 mmHg
PKA:4.03±0.10(Predicted)
Flash Point:148.8 °C
PSA：66.84000
Density:1.069 g/cm³
LogP:1.96250

Boc-N-methyl-L-valine(Cas 45170-31-8) Usage

Description	Boc-N-Me-Val serves as a versatile compound with applications in pharmaceutical intermediates, organic synthesis, and the construction of potential antitumor chemotherapeutic agents. Its role in peptide synthesis, protected by the Boc group, makes it valuable for controlled reactions in research and various chemistry applications.
Chemical Properties	White powder
Uses	Widely used in laboratories for synthesizing custom peptides, particularly in peptide chemistry research. Part of the toolkit of reagents and protecting groups used by chemists and biochemists in peptide synthesis.

InChI:InChI=1/C11H21NO4/c1-7(2)8(9(13)14)12(6)10(15)16-11(3,4)5/h7-8H,1-6H3,(H,13,14)/t8-/m1/s1

45170-31-8 Relevant articles

Synthetic studies on quinoxaline antibiotics: II. Synthesis of triostin A

Shin,Otsuka

, p. 2203 - 2210 (1984)

Triostin A, a cyclic octadepsipeptide, w...

First total synthesis of hoshinoamide A

Liu, Long,Rui, Zihan,Shao, Yutian,Xu, Shengtao,Yang, Yiming,Zhou, Haipin

supporting information, p. 2924 - 2931 (2022/01/12)

Hoshinoamides A, B and C, linear lipopep...

NOVEL CONNECTED BODY AND USE THEREOF IN SPECIFIC CONJUGATION BETWEEN BIOMOLECULE AND DRUG

-

Paragraph 0260-0261, (2021/05/14)

PROBLEM TO BE SOLVED: To provide: a meth...

Isolation and Total Synthesis of Kinenzoline, an Antitrypanosomal Linear Depsipeptide Isolated from a Marine Salileptolyngbya sp. Cyanobacterium

Kurisawa, Naoaki,Otomo, Keisuke,Iwasaki, Arihiro,Jeelani, Ghulam,Nozaki, Tomoyoshi,Suenaga, Kiyotake

, p. 12528 - 12536 (2021/09/20)

Kinenzoline (1), a new linear depsipepti...

CONJUGATION LINKERS CONTAINING 2,3-DIAMINOSUCCINYL GROUP

-

Page/Page column 210, (2020/05/19)

Provided is a conjugate of a cytotoxic d...

45170-31-8 Process route

: 22838-58-0
Boc-D-Val-OH

: 74-88-4
methyl iodide

: 13850-91-4,45170-31-8,89536-85-6
(R)-2-(tert-butoxycarbonyl(methyl)amino)-3-methylbutanoic acid

Conditions

Conditions	Yield
Boc-D-Val-OH; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere; methyl iodide; In tetrahydrofuran; mineral oil; at 20 ℃; for 36h; Inert atmosphere;	100%
With sodium hydride; In tetrahydrofuran; at 20 ℃; for 24h;	87.2%
Boc-D-Val-OH; methyl iodide; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere; With hydrogenchloride; In water; pH=2;	84%
With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 24h;	80%
With sodium hydride; In tetrahydrofuran;
With sodium hydride; In tetrahydrofuran; at 20 ℃;
With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 18h;
With sodium hydride; In tetrahydrofuran; at 20 ℃;
Boc-D-Val-OH; methyl iodide; In N,N-dimethyl-formamide; at 0 ℃; for 0.75h; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 5h;

: 640-68-6,25609-85-2,7004-03-7,921-10-8
D-Val-OH

: 24424-99-5
di-tert-butyl dicarbonate

: 74-88-4
methyl iodide

: 13850-91-4,45170-31-8,89536-85-6
(R)-2-(tert-butoxycarbonyl(methyl)amino)-3-methylbutanoic acid

Conditions

Conditions	Yield
D-Val-OH; di-tert-butyl dicarbonate; With sodium hydroxide; In 1,4-dioxane; methyl iodide; In tetrahydrofuran;

45170-31-8 Upstream products

1070-19-5
N-(tert-butyloxycarbonyl) azide
2480-23-1
N-methyl-L-valine
13734-41-3
t-Boc-L-valine
74-88-4
methyl iodide

45170-31-8 Downstream products

81135-38-8
benzyl (2S)-3-methyl-2-(methylamino)butanoate
203646-36-0
O-(tert-butoxycarbonyl)-N-methylvalyl-N-(benzyloxycarbonyl)threonyl-D-phenylalaninylprolylsarcosine tert-butyl ester
184104-29-8
(S)-benzyl 1-((S)-2-(tert-butoxycarbonyl(methyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate
24164-06-5
methyl (2S)-2-[(tert-butoxycarbonyl)(methyl)amino]-3-methylbutanoate