47931-85-1

Description

Calcitonin Salmon serves as a valuable therapeutic agent in various bone-related conditions, demonstrating efficacy in reducing bone resorption and managing calcium levels. Its applications extend to both clinical and research settings, offering insights into calcitonin receptor-related assays and stress-induced gastric mucosal barrier studies.

Calcitonin Salmon is a polypeptide hormone secreted by the ultimobranchial gland of salmon.
Belongs to the calcitonin-like protein family.
Synthetic analogue of salmon calcitonin (salcatonin), with a markedly different sequence compared to higher vertebrates.

Inhibits osteoclastic bone resorption, reducing serum calcium levels.
Increases renal excretion of phosphate, calcium, sodium, magnesium, and potassium by decreasing tubular reabsorption.
Acts as a hypocalcemic hormone produced by thyroid parafollicular C cells.
Regulates cAMP production and mammalian sperm function.
Stimulates bone formation and inhibits bone resorption in postmenopausal osteoporotic women.

Treatment of Paget's disease of bone.
Management of postmenopausal osteoporosis (fragile or brittle bones).
Emergency situations to quickly decrease serum calcium levels.
Added to existing therapeutic regimens for hypercalcemia.
Suitable for patients with azotemia or contraindications to intravenous fluids.

Chemical Properties

White or almost white powder.