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60117-17-1

  • Product NameMet-enkephalinamide
  • Molecular FormulaC27H36N6O6S
  • Molecular Weight572.685
  • Purity99%
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Product Details

Quick Details

  • CasNo: 60117-17-1
  • Molecular Formula: C27H36N6O6S
  • Purity: 99%

Factory Supply High Purity Met-enkephalinamide,Offer 60117-17-1 On Stock

  • Molecular Formula:C27H36N6O6S
  • Molecular Weight:572.685
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:142-145 °C 
  • Boiling Point:1066.7°C at 760 mmHg 
  • PKA:9.97±0.15(Predicted) 
  • Flash Point:598.9°C 
  • PSA:231.04000 
  • Density:1.303g/cm3 
  • LogP:1.90930 

Met-enkephalinamide(Cas 60117-17-1) Usage

General Description

Met-enkephalinamide is a naturally occurring opioid peptide and neuromodulator, acting as an agonist at μ-opioid receptors (μORs) and δ-opioid receptors (δORs). This pentapeptide, composed of five amino acids - methionine, enkephalin, and amide, functions as a neurotransmitter in both the central and peripheral nervous systems. Recognized for its analgesic properties, Met-enkephalinamide plays a key role in pain relief by binding to opioid receptors in the body.

Beyond its analgesic effects, Met-enkephalinamide is involved in regulating various physiological processes, including mood, stress responses, and immune function. Its significance extends to potential applications in the treatment of conditions such as chronic pain, addiction, and mood disorders. As an endogenous opioid peptide, Met-enkephalinamide underscores its importance in the body's natural mechanisms for pain modulation and overall neurophysiological regulation.

InChI:InChI=1/C27H36N6O6S/c1-40-12-11-21(25(29)37)33-27(39)22(14-17-5-3-2-4-6-17)32-24(36)16-30-23(35)15-31-26(38)20(28)13-18-7-9-19(34)10-8-18/h2-10,20-22,34H,11-16,28H2,1H3,(H2,29,37)(H,30,35)(H,31,38)(H,32,36)(H,33,39)/t20-,21-,22-/m0/s1

60117-17-1 Relevant articles

A new reagent, 2-[phenyl(methyl)sulfonio]ethyl-4-nitro-phenylcarbonate tetrafluoroborate (Pms-ONp), for preparing water-soluble N-protected amino acids

Hojo, Keiko,Maeda, Mitsuko,Takahara, Yuka,Yamamoto, Sachiko,Kawasaki, Koichi

, p. 2849 - 2851 (2003)

Peptide syntheses are performed in vario...

Solid-phase peptide synthesis in water. Part 3: A water-soluble N-protecting group, 2-[phenyl(methyl)sulfonio]ethoxycarbonyl tetrafluoroborate, and its application to solid phase peptide synthesis in water

Hojo, Keiko,Maeda, Mitsuko,Kawasaki, Koichi

, p. 1875 - 1886 (2007/10/03)

Chemical synthesis of peptides has been ...

Catalytic Transfer Hydrogenation in Pepetide Synthesis: Synthesis of 5- and 5-enkephalins

Sivanandaiah, K. M.,Gurusiddappa, S.

, p. 857 - 859 (2007/10/02)

The simplicity in the removal of N-prote...

SOLID-PHASE SYNTHETIC ROUTES TO ENKEPHALIN DERIVATIVES

Bello, Carlo Di,Lucchiari, Adriana,Buso, Orfeo

, p. 617 - 620 (2007/10/02)

The solid-phase synthesis of several ana...

60117-17-1 Process route

<Met-NH2><sup>5</sup>-enkephalin
60117-17-1

5-enkephalin

Conditions
Conditions Yield
With hydrogen fluoride; methoxybenzene; at 0 ℃; for 1h; Yield given;
 
Tyr-Gly-Gly-Phe-Met-NH<sub>2</sub>*HCOOH
84969-61-9

Tyr-Gly-Gly-Phe-Met-NH2*HCOOH

<Met-NH2><sup>5</sup>-enkephalin
60117-17-1

5-enkephalin

Conditions
Conditions Yield
With sodium hydrogencarbonate; In water; for 0.5h;
74%

60117-17-1 Upstream products

  • 84969-61-9
    84969-61-9

    Tyr-Gly-Gly-Phe-Met-NH2*HCOOH

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