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170941-79-4

  • Product NameFMOC-GLY-GLY-GLY-OH
  • Molecular FormulaC21H21N3O6
  • Molecular Weight411.40800
  • Purity99%
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Product Details

Quick Details

  • CasNo： 170941-79-4
  • Molecular Formula： C21H21N3O6
  • Purity： 99%

Factory Customized Supply High Purity 99% FMOC-GLY-GLY-GLY-OH 170941-79-4

  • Molecular Formula:C21H21N3O6
  • Molecular Weight:411.40800
  • Boiling Point:811.8±65.0 °C(Predicted) 
  • PKA:3.33±0.10(Predicted) 
  • PSA：133.83000 
  • Density:1.354±0.06 g/cm3(Predicted) 
  • LogP:2.01480 

FMOC-GLY-GLY-GLY-OH (Cas 170941-79-4) Usage

Description

 FMOC-GLY-GLY-GLY-OH is a chemical compound utilized in laboratory settings, particularly in peptide synthesis and proteomics studies.

Uses

 The entire sequence signifies a peptide composed of three glycine amino acids, with the C-terminus protected by the FMOC group. FMOC-GLY-GLY-GLY-OH serves as a cleavable ADC (antibody-drug conjugate) linker in the synthesis of ADCs. In proteomics studies and solid-phase peptide synthesis, Fmoc-Gly-Gly-OH, an Fmoc-protected glycine derivative, finds application. The FMOC group acts as a protective element during synthesis and can be subsequently removed to expose the free amino group.

 

170941-79-4 Relevant articles

Sol and gel states in peptide hydrogels visualized by Gd(III)-enhanced magnetic resonance imaging

Weerasekare, Mahika,Taraban, Marc B.,Shi, Xianfeng,Jeong, Eun-Kee,Trewhella, Jill,Yu, Yihua Bruce

, p. 734 - 743 (2011)

The hydrogels assembled from a pair of s...

Peptides and synthetic cell membranes

-

, (2008/06/13)

Linear peptides of the formula (I) R-A-B...

170941-79-4 Process route

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH
170941-79-4

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH

Conditions
Conditions Yield
With sodium carbonate; In tetrahydrofuran; at 0 - 20 ℃; for 4h;
100%
9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH
170941-79-4

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH

Conditions
Conditions Yield
 
  

170941-79-4 Upstream products

  • 556-33-2
    556-33-2

    glycine-glycine-glycine

  • 28920-43-6
    28920-43-6

    (fluorenylmethoxy)carbonyl chloride

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