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Product Details
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Description |
Fmoc-Arg(pbf)-Gly-OH is a chemical compound employed in peptide synthesis. |
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Uses |
Fmoc-Arg(pbf)-Gly-OH is commonly used in solid-phase peptide synthesis, a method in which peptides are assembled step by step on a solid support. The Fmoc group protects the amino group during synthesis and can be later removed, exposing the free amino group. The pbf group on arginine prevents unwanted reactions during synthesis and allows for selective deprotection when necessary. |
The synthesis of peptides for both resea...
Conjugates of porphyrin, chlorophyll and...
C36H42N5O8PolS
Fmoc-Arg(Pbf)-Gly-OH
| Conditions | Yield |
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With 2,2,2-trifluoroethanol; acetic acid; In dichloromethane; at 20 ℃; for 1h;
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Fmoc-glycine-2-chlorotrityl resin
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine
Fmoc-Arg(Pbf)-Gly-OH
| Conditions | Yield |
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Fmoc-glycine-2-chlorotrityl resin; With piperidine; In 2-methyltetrahydrofuran; for 0.166667h; 2-chlorotrityl chloride resin (CTC-resin)
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; With ethyl cyanoglyoxylate-2-oxime; diisopropyl-carbodiimide; In 2-methyltetrahydrofuran; at 20 ℃; for 1h; 2-chlorotrityl chloride resin (CTC-resin)
With trifluoroacetic acid; In 2-methyltetrahydrofuran; for 0.1h; 2-chlorotrityl chloride resin (CTC-resin)
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2.76 g |
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine
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