Dihexa is , while it's Molecular Formula is C 27 H 44 N 4 O 5 . Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease.

What is the CAS number for Dihexa?

The CAS number of Dihexa is 1401708-83-5.

What is Dihexa (1401708-83-5) used for?

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

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1401708-83-5

Product NameDihexa
Molecular FormulaC27H44N4O5
Molecular Weight504.67
Purity99%

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CasNo： 1401708-83-5
Molecular Formula： C27H44N4O5
Purity： 99%

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